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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2db50b32e5747faa8596b8bdb92efc227030faa24075c7285256aa8e9545aab0' 
  AND token = 'DMpiageGDEEgVAhFxy0XNX9zmxHoDX3JdbLuR22i/x8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}