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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '61a72de97afeb37148aa64210fc97c2668c7a69f71c228a8bfb77dbe6a110e28' 
  AND token = 'bZ3RnZ4P/4vrg7Jt1nQh0UqUo8AGfeRtiHEW0PLMLB4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}