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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6c8009324bd437039c6490755d716a3313d7e968871b2cc7a780be1f3ede3187' 
  AND token = '1xsLYFza/M1h9+X7Z5/8sq91fI3jcTFFgog0aHT9etQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}