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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '72561eb656910780253813b332b6c2203059ad1968be6ece319c4565ee7260cf' 
  AND token = 'It6lm7VsbF0vlPe27XXeH2Nt2cEBoUDc66s4PW6nl3w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}