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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'eaab4ed8afa2f29e961cffd31f76c0a7f73d0a9e2c37a0de654974a9042a022b' 
  AND token = '9l1atyhUB4cVqqvFdaH+vU/bKPJl4k3cpS4LoyOu6Mo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}