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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '99c9fd8c04d351fba575fd86606a24168d4e38bf8204af6d0caac1d6ccf9f8c5' 
  AND token = '0fnkKViREW3qr9LO1TKvtp19SfUpR+L97BM7DTH/ev8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}