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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7acea6279e3d22df47923cec1e8a2dcfa4c5e4ead1b21180f877f23066792098' 
  AND token = 'B39a1oCg1CvxJorOFPc+IzdVaEpW1Y2XcNwM89ix3bc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}