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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fb88397f1412e3c4055afdfb57dafb94d5182a82f3f33dc31e7da9f3de987527' 
  AND token = 'XZaYtCoFLIcN6NdKGfQNJ8mlqeLXpJ8D6sWOchIvki4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}