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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9bd588d011c4d819b63a35421d2bc87e3e8a1ca2e359b079d726846f1e4118d7' 
  AND token = 'SGQiBgSb1L67GsKkM1rfHev1BV84mA4ZzlykJC7HzTQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}