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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '65e7a1250d0d70100dee02163a933c5d80600622309b3ccb1dcbafa89319d4f4' 
  AND token = '1JyaYl6+kEy5pApiB3jS6s1dQLajjwruQ3JzNuHY8wQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}