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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '52e0ea890fbff0304dc8ee4dc92820baf64423fcb27e244817f50fff6d098428' 
  AND token = '/NRU0juts+5mo9eq1nm48Cif1WGFbxL46C/ocZyV2zA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}