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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e8b1d75f56227be46cb1f6f012eeb98d766056e9f77e3be0c302c77f3165fa20' 
  AND token = 'pwwIJ2zsACBUJquT13X9+lgYJONHEZUxALH7xbLYLe8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}