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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4639eeef1a5f332a5f19ac015ab091a27ef39698172fad6d99be5a4088498ca5' 
  AND token = 'NH9gKiFLwRNGcjWKgAOyEWwtEiP6QUnJ0iis/wGzo2k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}