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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3bd744e9025fbf4abba3f4a9b4b0a5c00c3d3520e270c62009574ee2c14466d2' 
  AND token = 'yrLBnIfUndENkJOhtnlvV7ffFJjCfIbNefxvjDcVIKs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}