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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bc2bc1c09743d9f1616e0775fb6c0decdc6c09d9dcbb0f3155d30644c3ea6fdb' 
  AND token = '4LAbh/mEG/LNRQmS3W+CKkQfd4bGkd27fBYwLvfv6JA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}