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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ec6488ec0063f0748f7d7451fdfd885b508aedcc290d4b28f73432fc45f228c9' 
  AND token = 'X2cGUwRj1LD8nyrgyxzL+rJekep1qep5vmLmdAr41Qc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}