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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b3e740730063d35b39e40f74ae7d849c9edd879cffa7a621a41bdbe3ff69d67f' 
  AND token = 'YqMyOm2kZbrRgMMGsyRUq17vMiFpjjDa/47Gx0hcjGI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}