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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ad25b5ef4ccc76dfff3307ec7c8d19bbb743e28caf571c4d3a1449895c06d681' 
  AND token = 'yo8bw+ffSR83RufO5jOsyL0hIKuuWcJ/wllRx6RvN9s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}