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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '53685815647f8e3556fada7480212dfbd569aee770584dc7e790ff0800f5fab2' 
  AND token = 'ndcieiBGIXs8YC94nEm0S4E97qDUvFfHXaCw5h88ysY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}