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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2dd17cc021ea255da0ea1e91c08bf1bb653b1b1253118cd914c2f859cebe6f9a' 
  AND token = '8xnssPuQmVqjoC1s6zmfe+1RrL4/zdvwBZrxkz4VTkc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}