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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4f31ce64d877e12d7de1c1d57fb4070c25d2baa3702504616c8a6e2187c3b37f' 
  AND token = 'HlKUelEMaZUrT1Uw6l/5WVO9klJbN48Tf36MuhIOC48=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}