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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd665acaa45205c9dd0400185ac2e321d68c4800ece613f36ef5c4f226313db5b' 
  AND token = 'k4vlLnO3wxauBPm8i5CARzF7hk4TFsj4yO/I+6rR8nY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}