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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7d70cf3d12252391ef6d4acddcc9ffc20f85613125cf850f403a0016620d90f4' 
  AND token = '+GZ5q0XivDVbMN5actK0/7jKSYfVPQV09QXX5ru6yig=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}