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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '54ef301ad3cd5fb840f66a243c0316ba20061ccfac47a20a9637b900a9a3475a' 
  AND token = '5Hvs7g6NRQQBzCkfrVav+hhmiGvM0Y+6KZN3bGS6oVE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}