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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd87caac25db13ce8f2d87ad1200e35c6ae11e45c9984faedf74a9bdbe1f6c1e9' 
  AND token = '3wSUhuOzqObOu4+kPPiw7yFoReSz8hVXrv7tgUMBL1Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}