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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e64d2e0be21d4494b0deff5d143d7087aa879fdeb0c2d3815748b134f51de7c2' 
  AND token = 'zFXFTsRjfWldwGN62/0xji8PcZRMpM8qCHsCgjq9Qvk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}