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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '138d3e62378e54f7c384e940319892a10b2a0224973cc601a1c8f6f2fb6cc388' 
  AND token = '0Kn7NFFBh848GaP8Nh0+LKnewIghvEUrb02ZX6vx+/Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}