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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '19421995e8f8ac2082268f1ef606dfa48957443212d5f6b7311b7a0eb04040ec' 
  AND token = 'UJdnCcxIwxxjkc4FVNE6jI2iB0Yqelk/3S3Z9A1dHiI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}