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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a17e5499b0fe599f5735448e7b044ca757d3d21dd26c7ff213d3c020f0fd23d3' 
  AND token = 'wc0FreUaZonB11GXA9s8Ak4Y+BVBDoVHsTn9vZCJDm4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}