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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '50aee9742caa39c2c4b5d1c5e5f4370570541b7742771e0241985fd794d6fada' 
  AND token = 'jdWwBXOMT3B5tKqjeFDdP56E+cFkTb5xf2eYl1h5a2w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}