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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3ceabe80c900c8f0ae4c2ee1bac0046ca35811a3ac6acf7fd9b752cf3b9730cb' 
  AND token = 'aXDqa03LISEdb3qk9Am3L8n+TKJ8CxLdLe3P4p9AxEU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}