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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8460527d23d12ce6af08c482d5dd35a9c3b812fc2359b4ff5db02520d0226a85' 
  AND token = '1SJlOeqqAgDY9kG5wv4AdPX53GtgMBzDlQ+5BxEO3UY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}