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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '22fbe81a12ec3fde5ad92aa9c431e61704cb9f10c7cf03639aeb4126a11018a9' 
  AND token = 'EIHezKbPM1CfnNyXojw0IjEzcN1CGQGRUoiBL9B/GoM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}