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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7853ef464a038a379bad6f0c0cad20e128261c55d6c9f6fe2697037d9aeb0a1c' 
  AND token = 'iYjtdmKToGaYwkn1k6h9XMFLPgwKmAIRg8rFS5Wkm3k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}