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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '926fe688a600fb034b69226f88eafc88cd31b51243e6aaa3c30ca23fb1b7c6bb' 
  AND token = '4QA1x3iq+c/w3E+6kQSVdy6NWSb27CBbFTCASe1mHDw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}