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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1e561bb4de43b2e4334777d0b22851b36335df501ad8e743a6d45881c00fb181' 
  AND token = 'YLLuDLqBbszlJ3KSLc/3krUFEUmLX4COQWjXd6AOeYA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}