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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '849c6846bc2ce43fb6e31a0f778a9ba36c26db8a862d7536ee7d1a69dbbf5760' 
  AND token = '1LVVgLXLGLXIxsNVd1YdaO9QvV8nO1wQS0pXC4rzVNw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}