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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '14b1ebd33c6ded849105431c96338b84f4f1bf47ebbf250fae7d6efe39ca178d' 
  AND token = 'yA2cIf1K8zbPn5K1mvZrMLm4dMi8Ld53K6lN1OmatK0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}