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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '41f7c2f538d2365947ea342be8723532f8890a5c40e34a7366baf49262882848' 
  AND token = 'RERyh00dTUfO09UhXjSuYwk9GzMARQRBrKwi/9IhYwM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}