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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '51f64a6560a446cbfe9edaff84abf9f3ce7169654e6f65eed4777e319d4e95ae' 
  AND token = 'c4QFXv5vWYsT0G/1sMJ+Bs10jpfx6fpvkETtYdLb+zk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}