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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dc916469dbe5c507a0a479f1b124dcde00a2144029eda14b43de2eea51b5d00e' 
  AND token = 'm815LQnypeU//rEYgkDJTrdbRT6HPxhMy5P4I/PkAHY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}