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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ac36d0bea2acf49ad4564e7302c16b5e9df6d6091b60a02567b6c31e1dca2c27' 
  AND token = 'GcJcOxv7R1L2Zq0QIHm2N7yV3DZXffPBcDn8SpSQcLE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}