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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3b871f55b4164a880c9b83efedbfdc997108d98ad9eb7e360b0be1f82fa42469' 
  AND token = 'GXcDzP77CRpjo5c5T9u8r3EzPr6bD3Jj4yY9NaPnGeE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}