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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e272573f25017722e7af1902bfeea6ef1e4d3fd14f1e6f92026f6ff86b4f3411' 
  AND token = 'vcM55TSXfm/HpGEEsdJIXm182d7d1/WyFSJbMMl6wTs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}