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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '100ef25873a75f44c8774e694b67060de8d3411576e0c49859e75ebc19f64319' 
  AND token = 'PfP1+e5uk2RYYYkLpm8OsSYvvkAuD2SQQdcVj96oTZU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}