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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '88f7396ce37e11d37dd8300e35cd212a8cc333d27d155aa9455b753343a05670' 
  AND token = '7Qk5rP8gjx2QHRLeCPXVgcfdF8UxvY/qt+UgEuVK9dg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}