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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dd018e47b53b31a42faf2efccdda22c98a3c9f533cb6f7093165b4e5f9024a7c' 
  AND token = 'xdvJMyqDPXOeU72NCYJfbsH/YkS3ryVmF5RoZoNtAUc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}