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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5c1deb2b255b0d3959122f2594e3d237825ce2fc7aa86b18c7eb4dcf5afae00f' 
  AND token = 'Cw+HjISm7KfKQn3A43LRLgo+oR9v0FXURcEm1lS/dKo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00040

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}