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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9f8cc3945827b17caab3a251bdd52c90894adf46122bd1aa0bc2f4ca3520a125' 
  AND token = 'KahmHAILE27g/VwTLI43iuyWR8LDP3b7KdaE3lWjrWs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}