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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8332f2c6f9446a14e5d50fce54ccf6671a18965e2ea555a0643f8271317bdec8' 
  AND token = '3EbN0VE0B51aQ/BfgbVasAhXtP+HmWr1jQcxOkCnHi0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}